Programme

 

 

Keynote Speakers:

KS-1. Alessandra Cambi, Radboud University (The Netherlands). Mechanobiology of immune cells: how stiffness and geometry of the extracellular environment influence myeloid cell properties.

KS-2. Ulrich Schwarz, Heidelberg University (Germany). Controlling cell contraction by optogenetics.

KS-3. José A. Sanz-Herrera, University of Seville (Spain). Monitoring the mechanical activity of cancer cells under normal, hypoxic and chemotherapeutic conditions.

KS-4. Hans Van Oosterwyck, KU Leuven (Belgium). Measuring cellular forces in 3D and application to microvascular disease.

KS-5. Corey Neu, University of Colorado Boulder (USA). Inverse modeling to map heterogeneous properties of the cell nucleus.

KS-6. Stéphane Avril, Ecole des Mines de Saint-Etienne (France). Bridging the gap between mechanobiology of aortic smooth muscle cells and biomechanics of aortic aneurysms.

KS-7. Xiaoyun Ding, University of Colorado Boulder (USA). High throughput mechanical disruption of plasma membrane and nuclear envelope for repair dynamics study.

KS-8. Patrick McGarry, NUI Galway (Ireland). Active contractility and remodelling of stress fibres and sarcomeres.

KS-9. Dennis Discher, University of Pennsylvania (USA). Pan-tissue scaling of mechanoregulated genes and heritable genetic changes in cancer.

KS-10. Vivek Shenoy, University of Pennsylvania (USA). How do forces from the cell’s environment affect DNA organization?

KS-11. Guillaume Charras, University College London (UK). The rupture strength of living cell sheets.

KS-12. Christian J. Cyron, TU Hamburg (Germany). What mechanical quantity do cells regulate in soft tissues?

KS-13. Ovijit Chaudhuri, Stanford (USA). Cell migration and morphogenesis in viscoelastic matrices

KS-14. Ben Fabry, Univ Erlangen-Nuremberg (Germany). High-throughput measurements of viscoelastic cell properties: Potential and limitations.

KS-15. Sandra Loerakker, TU Eindhoven (The Netherlands). Computational models to understand and advance the regeneration of engineered cardiovascular tissues.

KS-16. Debora Monego, Uni-Heidelberg (Germany). Exploring the evolutionary mechanisms of collagen as a protein material.

KS-17. Héctor Gómez, Purdue University (USA). Computational modeling of collective chemotaxis.

KS-18. Elisabeth Fischer-Friedrich, TU Dresden (Germany). Twofold mechanosensitivity ensures actin cortex reinforcement upon peaks in mechanical tension.

KS-19. Emad Moeendarbary, University College London (UK). Mechanics of cancer cell extravasation.

KS-20. Marino Arroyo, UPC (Spain). Collective invasion in strain-stiffening matrices by durolysis..

KS-21. Bart Smeets, KU Leuven (Belgium). Computational modeling of active foam dynamics in 3D tissues.

 

Oral Presentations:

OP-1. Alexander Mietke, Rui Ma. Emergent Morphologies of Active Surfaces.

OP-2. Dimosthenis Giannopoulos, Maja Schlittler, Marzia De Bortoli, Raffaele Coppini, Mina Petrovic, Elisabetta Cerbai, Gerhard Schütz, Philipp J. Thurner, Alessandra Rossini, Orestis G. Andriotis. Micromechanics of cardiac spheroids.

OP-3. Redowan A. Niloy, Guo–Jie J. Gao, Michael C. Holcomb, Jeffrey H. Thomas, Jerzy Blawzdziewicz. The role of tensile stress in the initiation and coordination of cephalic furrow formation in the drosophila embryo.

OP-4. Julio César Sánchez-Rendón, Annalena Reuss, Effie E. Bastounis. Apical shear stress impacts cell dynamics, kinematics and transcriptomic profile of three different endothelial cell types.

OP-5. Giulia Pozzi, Pasquale Ciarletta. Geometric control by active mechanics of epithelial gap closure.

OP-6. Pierre Ucla, Xingming Ju, Joanne Le Chesnais, Henri Ver Hulst, Ludovic Leconte, Jean Salamero, Catherine Monnot, Hélène Moreau, Jessem Landoulsi, Vincent Semetey, Sylvie Coscoy. Photopolymerization of 3D fiber networks to study the dynamics of cell-matrix interaction.

OP-7. Young Joon Suh, Mrinal Pandey, Alan T Li, Bangguo Zhu, Chung-Yuen Hui, Jeffrey E Segall, Mingming Wu. Tumor spheroid mechanics and invasion revealed by a microfluidic rheometer.

OP-8. Slav N. Bagriantsev, Elena O. Gracheva. 3D architecture and mechanism of touch detection by mechanosensory corpuscles.

OP-9. Jose Muñoz, Shafaq Zahra, Andrea Malandrino. Inference of cytoskeletal contractility from TFM data.

OP-10. Marie Muenkel, Erva Keskin, Aylin Balmes, Tilman Schäffer, Marco Lebtig, Dorothee Kretschmer, Kathryn Wright, Serge Mostowy, Effie Bastounis. Biomechanical alterations of endothelial cells exposed to bacterially-infected immune cells.

OP-11. Raquel B. Arroyo Vázquez, Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, Manuel Doblaré. Simulation of glioblastoma evolution in microfluidic devices with an agent-based model.

OP-12. Saber Shakibi, Erika Tsingos. Modeling the Impact of Cell-Matrix Mechanics on Migratory Heterogeneity in Cancer Metastasis.

OP-13. Edoardo Borgiani, Gabriele Nasello, Liesbet Geris. A novel in silico approach to investigate mechano-regulation of macrophages during bone fracture inflammatory stage.

OP-14. Ricardo Caballero, Miguel A. Martínez, Estefanía Peña. Hybrid approach for in-silico modelling of atherosclerosis: combining continuous and agent-based methods.

OP-15. Marina Pérez-Aliacar, Jacobo Ayensa-Jiménez, Manuel Doblaré. A continuum mathematical framework for modelling cellular adaptation and phenotypic plasticity in glioblastoma.

OP-16. Lauranne Maes, Thibault Vervenne, Amber Hendrickx, Ana C. Estrada, Lucas Van Hoof, Peter Verbrugghe, Filip Rega, Elizabeth A.V. Jones, Jay D. Humphrey, Nele Famaey. A computational study of pharmacological treatment after the ross procedure.

OP-17. J. Sarrate, E. Sala–Lardies, M. Pérez–Aliacar, J. Ayensa–Jiménez, M. Doblaré. Efficient numerical solution of a model for the evolution of glioblastoma cells.

OP-18. Maïté Marie Pétré, Greet Kerckhofs, Lauranne Maes, Nele Famaey. Meso-scale modelling of the arterial vessel wall.

OP-19. Shardool Kulkarni, Pablo Saez. Competing signaling pathways control electrotaxis.

OP-20. Claire C. Villette, Liesbet Geris. Modelling the influence of mechanical loading on the development of bone metastases using a hybrid cellular automaton.

OP-21. Rui DM Travasso, Soraia Melo, Pilar Guerrero, Maurício Moreira-Soares, José Rafael Bordin, Fátima Carneiro, João Carvalho, Joana Figueiredo, Raquel Seruca. The ECM and tissue architecture are major determinants of early invasion mediated by e-cadherin dysfunction.

OP-22. Gildas Carlin, Ian Manifacier, Jean-Louis Milan. Persistent random walk model of cell migration over curved surface.

OP-23. Satanik Mukherjee, Raphaelle Lesage, Laurens Spoelstra, Thanh Le, Carolina Serrano Larrea, Carlo Alberto Paggi, Jorge Barrasa Fano, Hans van Oosterwyck, Marcel Karperien, Liesbet Geris. A combinatorial in silico and in vitro approach to study cartilage mechanobiology using a cartilage-on-chip setup.

OP-24. Yogesh Saravanan, Sudiksha Mishra, Ramray Bhat, Claire Valotteau, Felix Rico. A semi automatised pipeline to measure the nano mechanics of complex samples.

OP-25. Xiangjun Peng, Ziyao Jia, Wenlong Xiao, Yuxuan Huang, Elliot L. Elson, Guy M. Genin, Xi-Qiao Feng. Recursive Cell-Matrix Feedback in Fibroblasts.

OP-26. Lara Hundsdorfer, David Jaworski, Marie Muenkel, Julio César Sánchez Rendón, Iordania Constantinou, Effie Bastounis. A live-cell imaging-compatible strteching device to study the influence of biomechanics on the interaction between bacterial pathogens and epithelia.

OP-27. Yousof MA Abdel-Raouf, Lauranne Maes, Mathias Peirlinck, Nele Famaey, Patrick Sips, Julie De Backer, Jonathan Weissmann, Jay D Humphrey, Patrick Segers. Mechanisms of maladaptation and the constrained mixture model.

 

Poster sessions:

P-1. Alejandro Apolinar-Fernández, Pablo Blázquez-Carmona, Raquel Ruíz-Mateos Brea, Jorge Barrasa-Fano, Hans Van Oosterwyck, Esther Reina-Romo, José Antonio Sanz-Herrera. Inverse traction reconstruction in 3D TFM: regularized and non-regularized methods.

P-2. Amlan Barai, Matis Soleilhac, Wang Xi, Shao-Zen Lin, Marc Karnat, Elsa Bazellières, Sylvie Richelme, Manuel Théry, Jean-François Rupprecht, Delphine Delacour. The emergence of “actin stars” for epithelium coordination and tissue patterning.

P-3. Ana Carrasco Mantis, Esther Reina-Romo, José Antonio Sanz-Herrera. An in silico study of a flow-enhanced vascularized organoid.

P-4. Alice Perucca, Andrea Gómez Llonin, Oriol Mañe Benach, Clement Hallopeau, Elisa I. Rivas, Jenniffer Linares, Marta Garrido, Anna Sallent-Aragay, Tom Golde, Julien Colombelli, Elena Dalaka, Judith Linacero, Marina Cazorla, Teresa Galan, Jordi Pastor Viel, Xavier Badenas, Alba Recort-Bascuas, Laura Comerma, Pere Roca-Cusachs, Joan Albanell, Xavier Trepat, Alexandre Calon, Anna Labernadie. Micro immune response on-chip (MIRO) model to study the spatial repartition of Immune cells in Tumor driven by Stromal Mechanosensing.

P-5. Apeksha Shapeti, Jorge Barrasa-Fano, Abdel Rahman Abdel Fattah, Janne de Jong, José Antonio Sanz-Herrera, Mylène Pezet, Said Assou, Emilie de Vet, Seyed Ali Elahi, Adrian Ranga, Eva Faurobert, Hans Van Oosterwyck. Force-mediated angiogenesis – a mechanism for vascular lesion growth.

P-6. Audrey Ntadambanya, Julien Pernier, Violaine David, Kimihiro Susumu, Igor L. Medintz, Mayeul Collot, A. Klymchenko, I. Le Potier, Niko Hildebrandt, Christophe Le Clainche, Marcelina Cardoso Dos Santos. Quantum-dot based nanosensors to study focal adhesion assembly and mechanosensing.

P-7. Beatrice Senigagliesi, Nassim Haffiane, Julien Sage, Pierre Nassoy, Rémi Galland, Grégory Giannone. Role of cell adhesion and cytoskeleton structures in three dimensional aggregates of small cell lung cancer cells.

P-8. Chandini Bhaskar Naidu, Bruno Goud, Stéphanie Miserey, Jean-Baptiste Manneville. Mechanotransduction at the golgi apparatus.

P-9. Erva Keskin, Mai Wang, Effie Bastounis. Apically applied fluid shear stresses are vasoprotective, decreasing the susceptibility of endothelial cells to infection with Listeria monocytogenes.

P-10. Jorge Barrasa-Fano, Alejandro Apolinar-Fernández, Laurens Kimps, Iain Muntz, Gijsje Koenderink, José Antonio Sanz-Herrera, Hans Van Oosterwyck. Novel data-driven method to measure cell forces in fibrillar hydrogels.

P-11. Juan José Toscano-Angulo, Juan Mora-Macías, Pablo Blázquez-Carmona, Juan Morgaz, Rocío Navarrete-Calvo, Jaime Domínguez, Esther Reina-Romo. BMD evolution during bone regeneration in osteoporotic bone.

P-12. Jyotsana Priyadarshani, Apeksha Shapeti, Jorge Barrasa Fano, Eva Faurobert, Hans Van Oosterwyck. Engineering ccm-associated mechanics on a microfluidic chip.

P-13. Lucie Jadrrna, Jaromir Gumulec, Jiri Bursa. Role of cytoskeleton in cancer cells under a variety of mechanical stimuli: a computational study.

P-14. Lucía López-de Abajo, Luis Saucedo-Mora, Francisco J. Montáns, José Mª Benítez. Influence of some genotypic parameters on the formation of necrotic cores in glioblastoma multiforme.

P-15. Nele Vaes, Maxim Vovchenko, Rocío Castro Viñuelas, Jorge Barrasa-Fano, Apeksha Shapeti, Ilse Jonkers, Hans Van Oosterwyck. Unraveling the mechanisms of traction force generation by chondrocytes and the effect of osteoarthritis.

P-16. Pablo Blázquez-Carmona, Fernando Rubio-Iglesias, Elisa Bevilacqua, Israel Valverde, Gorka Gómez-Ciriza, Ignacio González-Loscertales, Tarik Smani, Antonio Ordoñez, Esther Reina-Romo. Mechanical evaluation of 3d-printed vascular patches for congenital heart treatments.

P-17. Raquel Ruiz-Mateos, Pablo Blázquez-Carmona, Jorge Barrasa-Fano, Apeksha Shapeti, José Enrique Martín-Alfonso, Jaime Domínguez, Hans Van Oosterwyck, Esther Reina-Romo, José Antonio Sanz-Herrera. Hydrogels with tuneable collagen density regulate breast cancer cell mechanical activity.